I saw this in a company document.

Problem:
“Irregardless” is meaningless in that it means the opposite of what is intended.

Explanation:
People use “irregardless” when they mean the adverb “regardless”. The confusion could come from the fact that some words can be negated with the “ir” prefix. “Irreverent” is the opposite of “reverent”; “irregardless” is meaningless, on the other hand.

Solution:
“Regardless”